HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 21433688, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 4-Hydroxy-1-phenylcyclohexane-1-carbonitrile | HCID 12453673 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Product | HCID 21433688 | HCID 21433688 | — |
Reaction Steps
A thus produced 4-cyano-4-phenylcyclohexanol (b) obtained in step (1) is directly reduced, e.g., with lithium aluminum hydride (in a solvent such as tetrahydrofuran) at elevated (reflux) temperature, to give a corresponding 4-hydroxy-1-phenyl-1-cyclohexanecarboxaldehyde (c). This compound is also prepared via the tetrahydropyranyl ether of (b).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04025558 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-cafee28ed6aa484499b5d91aa5fa3260 |
| Source note | uspto-grants-1977_05 |