Ethanol → Sodium N-(4-methoxybenzoyl)-phenylalanyltyrosinate

HRID 2398858Notes

Reaction equation

HRID 2398858 reaction equation
[CH3:1][O:2][C:3]1[CH:34]=[CH:33][C:6]([C:7]([NH:9][C@H:10]([C:18]([NH:20][C@H:21]([C:30]([OH:32])=[O:31])[CH2:22][C:23]2[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=2)=[O:19])[CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:8])=[CH:5][CH:4]=1.C(O)C.[OH-].[Na+:39]>O>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:7]([NH:9][C@H:10]([C:18]([NH:20][C@H:21]([C:30]([O-:32])=[O:31])[CH2:22][C:23]2[CH:24]=[CH:25][C:26]([OH:29])=[CH:27][CH:28]=2)=[O:19])[CH2:11][C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)=[O:8])=[CH:33][CH:34]=1.[Na+:39]

Participants

5

Reactant 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 54084741N-(4-methoxybenzoyl)-phenylalanyltyrosine

Product 1

HCID 70615234Sodium N-(4-methoxybenzoyl)-phenylalanyltyrosinate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a solution of 0.9 g of N-(4-methoxybenzoyl)-phenylalanyltyrosine and 10 ml of ethanol, 10 ml of water was added. The mixture was adjusted to a pH of 8 with 1N sodium hydroxide and concentrated to dryness. Sodium N-(4-methoxybenzoyl)-phenylalanyltyrosinate in the form of a powder was obtained.

Workup

  1. concentrationconcentrated to dryness

Sources & evidence

ORD record
ord-b808b35c6e714fc6a35d6c4af7c653e6
Source dataset
uspto-grants-1977_05
Patent number
US04025644

Reaction notes

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