Dicyclohexylcarbodiimide → HCID 68117123, compound

HRID 2398877Notes

Reaction equation

HRID 2398877 reaction equation
[CH2:1]([N:4]1[CH2:9][C:8]2[C:10]3[C:21]([OH:22])=[CH:20][C:19]([CH:23]([CH:25]([CH3:31])[CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH3:24])=[CH:18][C:11]=3[O:12][C:13]([CH2:16][CH3:17])([CH2:14][CH3:15])[C:7]=2[CH2:6][CH2:5]1)[CH:2]=[CH2:3].[ClH:32].[N:33]1([CH2:39][CH2:40][CH2:41][C:42](O)=[O:43])[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34]1.C1(N=C=NC2CCCCC2)CCCCC1>>[ClH:32].[CH2:1]([N:4]1[CH2:9][C:8]2[C:10]3[C:21]([O:22][C:42](=[O:43])[CH2:41][CH2:40][CH2:39][N:33]4[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34]4)=[CH:20][C:19]([CH:23]([CH:25]([CH3:31])[CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH3:24])=[CH:18][C:11]=3[O:12][C:13]([CH2:16][CH3:17])([CH2:14][CH3:15])[C:7]=2[CH2:6][CH2:5]1)[CH:2]=[CH2:3]

Participants

4

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 131720814-(Piperidin-1-yl)butanoic acid hydrochlorideHCID 21418143HCID 21418143, compound

Product 1

HCID 68117123HCID 68117123, compound

Procedure

2-Allyl-5,5-diethyl-8-(3-methyl-2-octyl)-10-hydroxy-1,2,3,4-tetrahydro-5H-[1]-benzopyrano[3,4-d]-pyridine, γ-piperidinobutyric acid hydrochloride and dicyclohexylcarbodiimide are reacted in equimolar amounts to produce the desired product.

Sources & evidence

ORD record
ord-c7e9ca1ab89a4b88b91bf75dfc3c5921
Source dataset
uspto-grants-1977_05
Patent number
US04025630

Reaction notes

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