2-Fluorobenzoyl chloride → 6-[3'-Nitro-4'-(o-fluoro-benzoylamino)-phenyl]-4,5-dihydro-3(2H)-pyridazinone

Participants

Reaction Steps

11.7 gm of 6-(4'-amino-3'-nitro-phenyl)-4,5-dihydro-3(2H)-pyridazinone wereadded in small portions to a boiling solution of 15.8 gm of o-fluoro-benzoyl chloride in 350 ml of chlorobenzene, and the resulting mixture was heated for 15 hours more. After cooling, the reaction product was suction-filtered off and boiled with ethanol for purification.

Provenance & Evidence