Acetic Acid → HCID 21432165, compound

HRID 2398940Notes

Reaction equation

HRID 2398940 reaction equation
[CH3:1][CH:2]1[CH2:7][C:6]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15]([CH3:17])=[O:16])=[C:10]([N+:18]([O-])=O)[CH:9]=2)=[N:5][NH:4][C:3]1=[O:21].C(O)(=O)C>C(O)C>[CH3:1][CH:2]1[CH2:7][C:6]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:15]([CH3:17])=[O:16])=[C:10]([NH2:18])[CH:9]=2)=[N:5][NH:4][C:3]1=[O:21]

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 21432166HCID 21432166, compound

Product 1

HCID 21432165HCID 21432165, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.9 gm of 4-methyl-6-(3'-nitro-4'-acetamino-phenyl)-4,5-dihydro-3(2H)-pyridazinone were hydrogenated in 80 ml of ethanol and 20 ml of glacial acetic acid at room temperature and 5 atmospheres in the presence of 1.5 gm of palladizedcoal. The catalyst was then filtered off, the filtrate was evaporated, and the residue was used as such in the next step.

Workup

  1. customat room temperature
  2. filtrationThe catalyst was then filtered off
  3. customthe filtrate was evaporated

Sources & evidence

ORD record
ord-4cbbfa6aaef84b549e77c431d07eebda
Source dataset
uspto-grants-1977_05
Patent number
US04026891

Reaction notes

Loading…