Sodium Hydroxide → HCID 86734789, compound

HRID 2398947Notes

Reaction equation

HRID 2398947 reaction equation
[CH3:1][C:2](=[CH:16][C:17]1[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=1)[C:3]([NH:5][C:6]1[CH:7]=[C:8]([CH2:12][C:13]([OH:15])=[O:14])[CH:9]=[CH:10][CH:11]=1)=[O:4].[OH-].[Na+:25]>>[CH3:1][C:2](=[CH:16][C:17]1[CH:18]=[CH:19][C:20]([Cl:23])=[CH:21][CH:22]=1)[C:3]([NH:5][C:6]1[CH:7]=[C:8]([CH2:12][C:13]([O-:15])=[O:14])[CH:9]=[CH:10][CH:11]=1)=[O:4].[Na+:25]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 86734790HCID 86734790, compound

Product 1

HCID 86734789HCID 86734789, compound

Procedure

330 Milligrams of 3-(α-methyl-4'-chlorocinnamoylamino)phenylacetic acid were dissolved in an alcohol and an equivalent amount of sodium hydroxide was added to the solution. The solution was warmed for 30 minutes and then concentrated under reduced pressure. Ether was added to the residual liquid to precipitate crystals which were then collected by filtration to obtain sodium 3-(α-methyl-4'-chlorocinnamoylamino)phenylacetate.

Workup

  1. temperatureThe solution was warmed for 30 minutes
  2. concentrationconcentrated under reduced pressure
  3. additionEther was added to the residual liquid
  4. customto precipitate crystals which
  5. filtrationwere then collected by filtration

Sources & evidence

ORD record
ord-52236d00ff0e4c9baac7c1c4f932342e
Source dataset
uspto-grants-1977_05
Patent number
US04026896

Reaction notes

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