Sodium Hydroxide → HCID 23718706, compound

HRID 2398948Notes

Reaction equation

HRID 2398948 reaction equation
[CH3:1][C:2]1[CH:22]=[CH:21][C:5]([CH2:6][CH2:7][C:8]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[CH2:17][C:18]([OH:20])=[O:19])=[O:9])=[CH:4][CH:3]=1.[OH-].[Na+:24]>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][CH2:7][C:8]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[CH2:17][C:18]([O-:20])=[O:19])=[O:9])=[CH:21][CH:22]=1.[Na+:24]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 12818876HCID 12818876, compound

Product 1

HCID 23718706HCID 23718706, compound

Procedure

297 Milligrams of 2-(4'-methylhydrocinnamoylamino)phenylacetic acid were dissolved in an alcohol and an equivalent amount of sodium hydroxide was added to the solution. The solution was warmed for 30 minutes and then concentrated under reduced pressure. Ether was added to the residual liquid to precipitate crystals which were then collected by filtration to obtain sodium 2-(4'-methylhydrocinnamoylamino)phenylacetate.

Workup

  1. temperatureThe solution was warmed for 30 minutes
  2. concentrationconcentrated under reduced pressure
  3. additionEther was added to the residual liquid
  4. customto precipitate crystals which
  5. filtrationwere then collected by filtration

Sources & evidence

ORD record
ord-87a27acf3f1e46b6b2889eb2e088fcb7
Source dataset
uspto-grants-1977_05
Patent number
US04026896

Reaction notes

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