Sodium Hydroxide → HCID 86734791, compound

HRID 2398950Notes

Reaction equation

HRID 2398950 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:22]=[CH:23][CH:24]=1)[CH:6]=[CH:7][C:8]([NH:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[CH:17]([CH3:21])[C:18]([OH:20])=[O:19])=[O:9].[OH-].[Na+:26]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:22]=[CH:23][CH:24]=1)[CH:6]=[CH:7][C:8]([NH:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[CH:17]([CH3:21])[C:18]([O-:20])=[O:19])=[O:9].[Na+:26]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 86734792HCID 86734792, compound

Product 1

HCID 86734791HCID 86734791, compound

Procedure

162 Milligrams of 2-(3'-methoxycinnamoylamino)phenylpropionic acid were dissolved in an alcohol and an equivalent amount of sodium hydroxide was added to the solution. The mixture was warmed for 30 minutes and then concentrated under reduced pressure. The residue was taken up in a small amount of ethanol and ether was added to the ethanolic solution. The precipitated crystals were collected by filtration to obtain sodium 2-(3'-methoxycinnamoylamino)phenylpropionate.

Workup

  1. temperatureThe mixture was warmed for 30 minutes
  2. concentrationconcentrated under reduced pressure
  3. additionwas added to the ethanolic solution
  4. filtrationThe precipitated crystals were collected by filtration

Sources & evidence

ORD record
ord-4060da9058bd4930b89148b29e59f32e
Source dataset
uspto-grants-1977_05
Patent number
US04026896

Reaction notes

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