Sodium Hydroxide → HCID 68117626, compound

HRID 2398952Notes

Reaction equation

HRID 2398952 reaction equation
[OH:1][C:2]1[CH:22]=[CH:21][C:5]([CH:6]=[CH:7][C:8]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([CH2:17][C:18]([OH:20])=[O:19])=[CH:13][CH:12]=2)=[O:9])=[CH:4][CH:3]=1.[OH-].[Na+:24]>>[OH:1][C:2]1[CH:3]=[CH:4][C:5]([CH:6]=[CH:7][C:8]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([CH2:17][C:18]([O-:20])=[O:19])=[CH:13][CH:12]=2)=[O:9])=[CH:21][CH:22]=1.[Na+:24]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 54281562HCID 54281562, compound

Product 1

HCID 68117626HCID 68117626, compound

Procedure

289 Milligrams of 4-(4'-hydroxycinnamoylamino)phenylacetic acid were dissolved in an alcohol and an equivalent amount of sodium hydroxide was added to the solution. The solution was warmed for 30 minutes and then concentrated under reduced pressure. Ether was added to the residue and the precipitated crystals were collected by filtration to obtain sodium 4-(4'-hydroxycinnamoylamino)phenylacetate.

Workup

  1. temperatureThe solution was warmed for 30 minutes
  2. concentrationconcentrated under reduced pressure
  3. additionEther was added to the residue
  4. filtrationthe precipitated crystals were collected by filtration

Sources & evidence

ORD record
ord-c6bdd1d0813742168f16f2f7bd656206
Source dataset
uspto-grants-1977_05
Patent number
US04026896

Reaction notes

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