Ethyl 1-methyl-5-nitro-2-imidazolecarboxylate thiosemicarbazone → Megazol

HRID 2399006Notes

Reaction equation

HRID 2399006 reaction equation
[CH3:1][N:2]1[C:6]([N+:7]([O-:9])=[O:8])=[CH:5][N:4]=[C:3]1[C:10]([NH:12][NH:13][C:14]([NH2:16])=[S:15])=N.CN1C([N+]([O-])=O)=CN=C1C(=NNC(N)=S)OCC>>[NH2:16][C:14]1[S:15][C:10]([C:3]2[N:2]([CH3:1])[C:6]([N+:7]([O-:9])=[O:8])=[CH:5][N:4]=2)=[N:12][N:13]=1

Participants

3

Reactant 2

HCID 54213536Ethyl 1-methyl-5-nitro-2-imidazolecarboxylate thiosemicarbazoneHCID 178481319HCID 178481319, compound

Product 1

HCID 29698Megazol

Procedure

In a similar manner, acid treatment of the mixture of 1-(1-methyl-5-nitro-2-imidazolecarboximidoyl)-3-thiosemicarbazide and ethyl 1-methyl-5-nitro-2-imidazolecarboxylate thiosemicarbazone, gives the title compound.

Sources & evidence

ORD record
ord-96624dfe95934702a66bfcee7853bb3b
Source dataset
uspto-grants-1977_05
Patent number
US04026903

Reaction notes

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