HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 3-(3-Nitro-4-chlorobenzoyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | Potassium Nitrate | HCID 24434 | — |
| Reactant | 4-Chlorophenyl pyridin-3-yl ketone | HCID 84518 | — |
| Product | 3-(3-Nitro-4-chlorobenzoyl)pyridine | HCID 21432600 | — |
Reaction Steps
15.5 g. (0.153 mol) of potassium nitrate was added portion-wise to a stirred solution of 33 g. (0.152 mol) of 3-(4-chlorobenzoyl)pyridine in 200 ml. of sulfuric acid while maintaining the temperature below 40° . After 1 hr. the mixture was cautiously poured into 2 liters of ice-water, neutralized with ammonium hydroxide and the product collected to yield 3-(3-nitro-4-chlorobenzoyl)pyridine as yellow prisms, mp. 112° -113° C. (carbon tetrachloride-Norite).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04026936 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-b761b77eee11418cb657b42574b29685 |
| Source note | uspto-grants-1977_05 |