反应详情

A suspension of 63 g. (0.24 mol) of 3-(3-nitro-4-chlorobenzoyl)pyridine in 3 liters of a saturated solution of ammonia in ethanol was autoclaved at 100° C. for 24 hours. The mixture was concentrated in vacuo and the resulting residue dissolved in 1.5 liters of warm 5N HCl. The solution was cooled to room temperature and neutralized with concentrated ammonium hydroxide. The resulting product was collected as yellow-orange prisms, mp. 229° -230° C. (dimethylformamide-2-propanol).

1. additionA suspension of 63 g
2. concentrationThe mixture was concentrated in vacuo
3. dissolutionthe resulting residue dissolved in 1.5 liters of warm 5N HCl
4. customThe resulting product was collected as yellow-orange prisms, mp. 229° -230° C. (dimethylformamide-2-propanol)