HCID 21432597, compound → HCID 21432585, compound

Participants

Reaction Steps

A suspension of 20 g. (0.082 mol) of 4-(3-nitro-4-aminobenzoyl)pyridine in 1 liter of tetrahydrofuran containing 5 g. of 5% palladium on carbon was reduced with hydrogen under a pressure of 3 atmospheres. The resulting mixture was filtered and concentrated in vacuo to reddish oil which was dissolved in a minimum amount of methylene chloride and diluted with petroleum ether to yield 4-(3,4-diaminobenzoyl)pyridine as an unstable orange solid, mp. 210° -214° C. (water-Norite).

Provenance & Evidence