HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromophenyl isocyanate → 1-(4-Bromophenyl)-3-(1-pyrrolin-2-yl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromophenyl isocyanate | HCID 75609 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 2-Amino-1-pyrroline hydrochloride | HCID 12778905 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-(4-Bromophenyl)-3-(1-pyrrolin-2-yl)urea | HCID 21406183 | — |
Reaction Steps
Following a procedure similar to that described in Example 2 but using 4.6 g. sodium in 300 ml. dry acetone, 23.2 g. 2-amino-1-pyrroline hydrochloride and 38.9 g. 4-bromophenyl isocyanate in 200 ml. dry acetone, there was obtained after recrystallization from ethyl alcohol 10.8 g. of the hydrochloride of 1-(4-bromophenyl)-3-(1-pyrrolin-2-yl)urea; m.p. 221°-224° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04026938 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-46c563436fe24306b7e938638745ebba |
| Source note | uspto-grants-1977_05 |