HCID 21432737, compound → HCID 21432715, compound

HRID 2399111Notes

Reaction equation

HRID 2399111 reaction equation
C(OC([NH:11][C:12]1[CH:13]=[C:14]2[C:19](=[CH:20][CH:21]=1)[N:18]=[N:17][C:16]([C:22]([O:24][CH2:25][CH3:26])=[O:23])=[CH:15]2)=O)C1C=CC=CC=1.[H][H]>[Pd].C(O)C>[NH2:11][C:12]1[CH:13]=[C:14]2[C:19](=[CH:20][CH:21]=1)[N:18]=[N:17][C:16]([C:22]([O:24][CH2:25][CH3:26])=[O:23])=[CH:15]2

Participants

5

Reactant 2

HCID 21432737HCID 21432737, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 21432715HCID 21432715, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Palladium on charcoal catalyst (30% w/w; 100 mg.) was added to a solution of ethyl 6-(benzyloxycarbonylamino)-cinnolin-3-yl carboxylate (1 g.) in dry ethanol (25 ml.). The solution was shaken in an atmosphere of hydrogen at room temperature and atmospheric pressure for 24 hours. The mixture was filtered and the filtrate evaporated in vacuo to give, as solid residue, ethyl 6-aminocinnolin-3-yl carboxylate.

Workup

  1. filtrationThe mixture was filtered
  2. customthe filtrate evaporated in vacuo

Sources & evidence

ORD record
ord-29b4eac8678348a1acf15942c31af571
Source dataset
uspto-grants-1977_05
Patent number
US04027023

Reaction notes

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