4-(N-Propionylaniline)piperidine → HCID 53760428, compound

HRID 2399175Notes

Reaction equation

HRID 2399175 reaction equation
[C:1]([NH:4][C:5]1[CH:14]=[CH:13][C:8]([O:9][CH2:10][CH2:11]Br)=[CH:7][CH:6]=1)(=[O:3])[CH3:2].[C:15]1([N:21]([CH:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[C:22](=[O:25])[CH2:23][CH3:24])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[C:1]([NH:4][C:5]1[CH:14]=[CH:13][C:8]([O:9][CH2:10][CH2:11][N:29]2[CH2:28][CH2:27][CH:26]([N:21]([C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)[C:22](=[O:25])[CH2:23][CH3:24])[CH2:31][CH2:30]2)=[CH:7][CH:6]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 2593814-(N-Propionylaniline)piperidineHCID 6483715N-(4-(2-Bromoethoxy)phenyl)acetamide

Product 1

HCID 53760428HCID 53760428, compound

Procedure

Using the procedure of Example I step B and starting from (4-acetamidophenoxyethyl) bromide and 4-(N-phenyl N-propionylamino) piperidine, N-[(4-acetamidophenoxy) ethyl] 4-(N'-phenyl N'-propionylamino) piperidine is obtained which melts at 78°.

Sources & evidence

ORD record
ord-b1d4481a19c6451d8837c045950b7fc0
Source dataset
uspto-grants-1977_05
Patent number
US04027028

Reaction notes

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