4-(N-Propionylaniline)piperidine → HCID 86734811, compound

HRID 2399176Notes

Reaction equation

HRID 2399176 reaction equation
[O:1]1[C:10]2[S:9][CH2:8][CH:7]=[CH:6][C:5]=2[CH2:4][CH2:3][CH:2]1[O:11][CH2:12][CH2:13]Br.[C:15]1([N:21]([CH:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[C:22](=[O:25])[CH2:23][CH3:24])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[O:1]1[C:10]2[S:9][CH2:8][CH:7]=[CH:6][C:5]=2[CH2:4][CH2:3][CH:2]1[O:11][CH2:12][CH2:13][N:29]1[CH2:28][CH2:27][CH:26]([N:21]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)[C:22](=[O:25])[CH2:23][CH3:24])[CH2:31][CH2:30]1

Participants

3

Reactant 2

HCID 2593814-(N-Propionylaniline)piperidineHCID 68123412HCID 68123412, compound

Product 1

HCID 86734811HCID 86734811, compound

Procedure

Using the procedure of Example I step B and starting from (8-thiachromanyloxyethyl) bromide and 4-(N-phenyl N-propionylamino) piperidine, N (8-thiachromanyloxyethyl) 4-(N'-phenyl N'-propionylamino) piperidine is obtained and isolated as its oxalate which melts at 182°-184°.

Sources & evidence

ORD record
ord-99cb167987094dadb62ef29a4c0a162a
Source dataset
uspto-grants-1977_05
Patent number
US04027028

Reaction notes

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