(3-Propoxyphenyl)boronic acid → 5-Bromo-2-(3-propoxyphenyl)pyrimidine

HRID 2399204Notes

Reaction equation

HRID 2399204 reaction equation
Br[C:2]1[N:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=1.[CH2:9]([O:12][C:13]1[CH:14]=[C:15](B(O)O)[CH:16]=[CH:17][CH:18]=1)[CH2:10][CH3:11]>>[Br:8][C:5]1[CH:4]=[N:3][C:2]([C:17]2[CH:16]=[CH:15][CH:14]=[C:13]([O:12][CH2:9][CH2:10][CH3:11])[CH:18]=2)=[N:7][CH:6]=1

Participants

3

Reactant 2

HCID 3691230(3-Propoxyphenyl)boronic acidHCID 109555882,5-Dibromopyrimidine

Product 1

HCID 193862315-Bromo-2-(3-propoxyphenyl)pyrimidine

Procedure

2,5-Dibromopyrimidine and 3-propoxybenzeneboronic acid are reacted analogously to Example 1 to give 5-bromo-2-(3-propoxyphenyl) pyrimidine. ##STR40##

Sources & evidence

ORD record
ord-e5e60a6d4b304ded8da96d8336e254c0
Source dataset
uspto-grants-1995_09
Patent number
US05447656

Reaction notes

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