4-Benzyloxy-phenylboronic acid → HCID 19386216, compound

HRID 2399205Notes

Reaction equation

HRID 2399205 reaction equation
Br[C:2]1[CH:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([O:14][CH2:15][CH2:16][CH3:17])[CH:9]=2)=[N:6][CH:7]=1.[CH2:18]([O:25][C:26]1[CH:31]=[CH:30][C:29](B(O)O)=[CH:28][CH:27]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:18]([O:25][C:26]1[CH:31]=[CH:30][C:29]([C:2]2[CH:3]=[N:4][C:5]([C:8]3[CH:13]=[CH:12][CH:11]=[C:10]([O:14][CH2:15][CH2:16][CH3:17])[CH:9]=3)=[N:6][CH:7]=2)=[CH:28][CH:27]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 27343144-Benzyloxy-phenylboronic acidHCID 193862315-Bromo-2-(3-propoxyphenyl)pyrimidine

Product 1

HCID 19386216HCID 19386216, compound

Procedure

5-Bromo-2-(3-propoxyphenyl)pyrimidine and 4-benzyloxybenzeneboronic acid (preparation analogous to 3-benzyloxybenzeneboronic acid) are reacted analogously to Example 1 to give 5-(4-benzyloxyphenyl)-2-(3-propoxyphenyl)pyrimidine. ##STR41##

Sources & evidence

ORD record
ord-bd8a1e0758fe48f3a5d33959df1f19a2
Source dataset
uspto-grants-1995_09
Patent number
US05447656

Reaction notes

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