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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2399209Generated: October 31, 2026

(+)-Solketal → 5-[4-((4S)-2,2-Dimethyl-1,3-dioxolan-4-ylmethoxy)phenyl]-2-(3-propoxyphenyl)pyrimidine

https://huagongshe.com/reaction/2399209

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+)-SolketalHCID 736057—
Reactant5-(4-Hydroxyphenyl)-2-(3-propoxyphenyl)pyrimidineHCID 19386214—
SolventChloroformHCID 6212—
Product5-[4-((4S)-2,2-Dimethyl-1,3-dioxolan-4-ylmethoxy)phenyl]-2-(3-propoxyphenyl)pyrimidineHCID 57017922—

Reaction Steps

The synthesis is carried out analogously to Example 17 from 5-(4-hydroxyphenyl)-2-(3-propoxyphenyl)pyrimidine and (4S )-2,2-dimethyl-1,3-dioxolan-4-ylmethanol (commercially available). ##STR46## [α]D20 (CHCl3)=+5.0

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05447656
Source datasetuspto-grants-1995_09
ORD IDord-0435c6000b70445eaed6a27c4415679c
Source noteuspto-grants-1995_09