HCID 10765220, compound → HCID 57255911, compound

HRID 2399345Notes

Reaction equation

[F:1][C:2]([F:34])([F:33])[C:3]1[CH:8]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:6]=[CH:5][C:4]=1CCCCCCC(=O)CC(O)(C(OC)=O)CC(OC)=O.ClC1C=C(Cl)C=CC=1[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][C:49](=[O:62])[CH2:50][C:51]([OH:61])([C:57]([O:59]C)=O)[CH2:52][C:53]([O:55]C)=[O:54]>>[F:1][C:2]([F:34])([F:33])[C:3]1[CH:8]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:6]=[CH:5][C:4]=1[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][C@@H:49]1[O:62][C:57](=[O:59])[C@@:51]([CH2:52][C:53]([OH:55])=[O:54])([OH:61])[CH2:50]1

Participants

Reactant 2

HCID 10765220HCID 10765220, compound

HCID 54159139HCID 54159139, compound

Product 1

HCID 57255911HCID 57255911, compound

Procedure

Following the procedures described in examples 1 (g) and 2, substituting ±methyl 11-[2,4-Bis (trifluoromethyl)phenyl]-3-hydroxy-3-methoxycarbonyl-5-oxo-undecanoate for ± methyl 11(2,4-dichlorophenyl )-3-hydroxy-3-methoxycarbonyl-5-oxo-undecanoate, gave the title compound as a solid, m.p. 70°-73° C.

Sources & evidence

ORD record: ord-a3d9d65d3f174a7dab1eaecd05a9cfd4
Source dataset: uspto-grants-1995_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05447954

Reaction notes

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