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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2399349Generated: October 31, 2026

Ethyl 4-bromobutyrate → HCID 2885531, compound

https://huagongshe.com/reaction/2399349

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-bromobutyrateHCID 76300—
ReactantUmbelliferoneHCID 5281426—
ProductHCID 2885531HCID 2885531—

Reaction Steps

Coumarin-7-oxybutyric acid N-hydroxysuccinimide ester was prepared by reacting 7-hydroxycoumarin with ethyl 4-bromobutyrate to form coumarin-7-oxybutyric acid ethyl ester. Next, the ethyl ester was reacted with acid to form coumarin-7-oxybutyric acid which was reacted with N-hydroxysuccinimide to form the N-hydroxysuccinimide ester in accordance with the Scheme 1 above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05449602
Source datasetuspto-grants-1995_09
ORD IDord-08d84931f119465292cfd32641025c98
Source noteuspto-grants-1995_09