Ethyl (7-methoxynaphthalen-1-yl)acetate → (7-Methoxynaphthalen-1-yl)acetic acid

HRID 2399384Notes

Reaction equation

HRID 2399384 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([O:16]CC)=[O:15])=[CH:5][CH:4]=1>[OH-].[Na+].C(O)C>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([OH:16])=[O:15])=[CH:5][CH:4]=1

Participants

4

Reactant 1

HCID 13570063Ethyl (7-methoxynaphthalen-1-yl)acetate

Product 1

HCID 13570105(7-Methoxynaphthalen-1-yl)acetic acid

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

A mixture of the ethyl 7-methoxynaphth-1-ylacetate obtained above in 250 cm3 of 20% sodium hydroxide in ethanol is refluxed for 3 hours.

Workup

  1. temperatureis refluxed for 3 hours

Sources & evidence

ORD record
ord-65dea57bea2743fb89316bd11faa72fb
Source dataset
uspto-grants-1995_09
Patent number
US05449689

Reaction notes

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