HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 2-(7-Methoxynaphthalen-1-yl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Trifluoroacetic anhydride | HCID 9845 | — |
| Reactant | 2-(7-Methoxynaphthalen-1-yl)acetamide | HCID 15149127 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(7-Methoxynaphthalen-1-yl)acetonitrile | HCID 11264068 | — |
Reaction Steps
The (7-methoxynaphth-1-yl)acetamide obtained in step E is suspended in 80 cm3 of anhydrous tetrahydrofuran. Triethylamine is added. The solution is cooled in an ice bath, and then trifluoroacetic anhydride is added dropwise, with magnetic stirring.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05449689 |
| Source dataset | uspto-grants-1995_09 |
| ORD ID | ord-22402018273349c8af6ddc9b23d2aa6e |
| Source note | uspto-grants-1995_09 |