Ethyl (7-methoxynaphthalen-1-yl)acetate → (7-Methoxynaphthalen-1-yl)acetic acid
Reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([O:16]CC)=[O:15])=[CH:5][CH:4]=1>[OH-].[Na+].C(O)C>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([OH:16])=[O:15])=[CH:5][CH:4]=1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
A mixture of the ethyl 7-methoxynaphth-1-ylacetate obtained above in 250 cm3 of 20% sodium hydroxide in ethanol is refluxed for 3 hours.
Workup
- temperatureis refluxed for 3 hours
Sources & evidence
- ORD record
- ord-6ac053e14cc94bbdb248ead806de8ead
- Source dataset
- uspto-grants-1995_09
- Patent number
- US05449690
Reaction notes
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