HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → HCID 19385679, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | 2-(1-Methylcyclohexyl)-p-cresol | HCID 85304 | — |
| Reactant | Methyl 2-(2-bromophenyl)acetate | HCID 8063364 | — |
| Reactant | Acetone potassium carbonate | HCID 86600397 | — |
| Product | HCID 19385679 | HCID 19385679 | 91.2% |
Reaction Steps
Using the K2CO3 /acetone conditions for phenol alkylation described in Step A of Example 30, 0.496 g (2.4.3 mmol) of 2-(1-methylcyclohex-1-yl)-4-methylphenol was alkylated with 0.834 g (3.64 mmol) of methyl 2-bromophenylacetate to afford 0.780 g (91%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05449682 |
| Source dataset | uspto-grants-1995_09 |
| ORD ID | ord-c40bbcb33cd544adbf51fb8a6fd66ca1 |
| Source note | uspto-grants-1995_09 |