HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → HCID 178437532, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | 2-ethyl-7-methyl-3H-Imidazo[4,5-b]pyridine | HCID 18693036 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 178437532 | HCID 178437532 | 96.6% |
Reaction Steps
A solution of 28 g (174 mmol) of 2-ethyl-7-methylimidazo[4,5-b]pyridine (described in European Patent Application #400,974, May 12, 1990) and m-chloroperbenzoic acid (80-90%, 44.6 g) in CHCl3 (300 mL) was heated at reflux for 0.5 hours. The mixture was concentrated and purified (SiO2, 100% CH2Cl2 gradient to 30% CH2Cl2 /MeOH) to give 29.8 g of the title compound as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05449682 |
| Source dataset | uspto-grants-1995_09 |
| ORD ID | ord-642cdb84c7104d4a8d7148d6458d6de6 |
| Source note | uspto-grants-1995_09 |