6-Chloro[1,3]dioxolo[4,5-f][1,3]benzothiazole → HCID 178527754, compound

HRID 2399724Notes

Reaction equation

HRID 2399724 reaction equation
Cl[C:2]1[S:3][C:4]2[CH:10]=[C:9]3[O:11][CH2:12][O:13][C:8]3=[CH:7][C:5]=2[N:6]=1.NC(N)=[S:16]>C(O)C>[SH:16][C:2]1[S:3][C:4]2[CH:10]=[C:9]3[O:11][CH2:12][O:13][C:8]3=[CH:7][C:5]=2[N:6]=1

Participants

4

Reactant 2

HCID 20498846-Chloro[1,3]dioxolo[4,5-f][1,3]benzothiazoleHCID 2723790Thiourea

Product 1

HCID 178527754HCID 178527754, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The product from Step 2 (0.67 g) and thiourea (0.26 g) were mixed in ethanol (20 cm3) and stirred and heated to reflux under an atmosphere of nitrogen for 18 hr. The pale yellow solid which precipitated was filtered from the solution at ambient temperature, washed with ethanol and sucked to dryness to give the required product. 1H NMR (DMSO): δ7.26(1H,s); 6.80(1H,s); 6.02(2H,s); mp 265° C. (dec); M+ =211.

Workup

  1. temperatureheated
  2. temperatureto reflux under an atmosphere of nitrogen for 18 hr
  3. customThe pale yellow solid which precipitated
  4. filtrationwas filtered from the solution at ambient temperature
  5. washwashed with ethanol

Sources & evidence

ORD record
ord-0d8b9693e20043679f50682ffbbf8374
Source dataset
uspto-grants-1995_09
Patent number
US05451594

Reaction notes

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