2,2-Dimethylcyclohexan-1-one → HCID 67784827, compound

HRID 2399783Notes

Reaction equation

HRID 2399783 reaction equation
Cl.[C:2]([C:7]1[C:12]([NH:13]N)=[CH:11][CH:10]=[CH:9][CH:8]=1)([O:4][CH2:5][CH3:6])=[O:3].[CH3:15][C:16]1([CH3:23])[CH2:21][CH2:20][CH2:19][CH2:18][C:17]1=O>C(O)(=O)C>[CH2:5]([O:4][C:2]([C:7]1[CH:8]=[CH:9][CH2:10][C:11]2[C:12]=1[N:13]=[C:18]1[CH2:19][CH2:20][CH2:21][C:16]([CH3:23])([CH3:15])[C:17]=21)=[O:3])[CH3:6]

Participants

4

Reactant 2

HCID 1369292,2-Dimethylcyclohexan-1-oneHCID 19384589HCID 19384589, compound

Product 1

HCID 67784827HCID 67784827, compoundYield 58.1%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Using the procedure of Example 1, the reaction of 29.0 g of 6-carbethoxyphenylhydrazine hydrochloride with 16.9 g of 2,2-dimethylcyclohexanone in 250 ml of 80% aqueous acetic acid afforded 21.1 g (58%) of 1,2,3,4-tetrahydro-1,1-dimethyl-9H-dibenzo [b,d]pyrrole-6-carboxylic acid ethyl ester as an orange solid after chromatographic purification.

Sources & evidence

ORD record
ord-95fca1585f834ecf814b4ca2f713f56d
Source dataset
uspto-grants-1995_09
Patent number
US05451600

Reaction notes

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