5-acetyl-2-Furancarboxylic acid methyl ester → (E)-5-[1-methyl-2-(1,2,3,4-tetrahydro-9-octyl-9H-dibenzo[b,d]pyrrol-6-yl)ethenyl]-2-furan carboxylic acid methyl ester

Participants

Reaction Steps

Using the conditions described in Example 37, the Wittig condensation reaction of 2.8 g of the phosphonium salt from Example 26 with 0.76 g of 5-acetyl-2-furancarboxylic acid methyl ester from Example 45 produced 1.0 g (52.5%) of (E)-5-[1-methyl-2-(1,2,3,4- tetrahydro-9-octyl-9H-dibenzo[b,d]pyrrol-6-yl)ethenyl]-2-furan carboxylic acid methyl ester as a yellow oil after chromatographic purification.

Provenance & Evidence