Ethyl Acetate → HCID 19384512, compound

Participants

Reaction Steps

The hydrogenation of 1,2,3,4-tetrahydro-6-phenylmethoxy-9-octyl-9H-dibenzo[b,d]pyrrole from Example 63 was carried out at atmospheric pressure and at room temperature. Thus, 12.5 g of this material dissolved in 125 mL of absolute ethanol and 75 mL of ethyl acetate was hydrogenated in the presence of 0.6 g of 10% Palladium on carbon. The mixture was filtered on celite, the solvents evaporated in vacuo and the residue was chromatographed on silica gel to give 9.5 g (98.5%) of 1,2,3,4-tetrahydro-9-octyl-9H-dibenzo[b,d]pyrrol-3-ol as a yellow oil.

Provenance & Evidence