2-Furancarboxylic acid → HCID 19384536, compound

HRID 2399803Notes

Reaction equation

HRID 2399803 reaction equation
C[O:2][C:3]([C:5]1[O:6][C:7]([O:10][C:11]2[CH:12]=[C:13]3[N:17]=[C:16]4[CH2:18][CH2:19][CH2:20][CH2:21][C:15]4=[C:14]3[CH:22]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[CH:23]=2)=[CH:8][CH:9]=1)=[O:4].O1C=CC=C1C(O)=O>>[CH2:24]([CH:22]1[C:14]2=[C:15]3[CH2:21][CH2:20][CH2:19][CH2:18][C:16]3=[N:17][C:13]2=[CH:12][C:11]([O:10][C:7]2[O:6][C:5]([C:3]([OH:4])=[O:2])=[CH:9][CH:8]=2)=[CH:23]1)[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31]

Participants

3

Reactant 2

HCID 69192-Furancarboxylic acidHCID 67784438HCID 67784438, compound

Product 1

HCID 19384536HCID 19384536, compound

Procedure

Using the procedure of Example 43, 6.3 g of the methyl ester from Example 110 was saponified to 5-(1,2,3,4-tetrahydro-9-octyl-9H-dibenzo[b,d]pyrrol-7-yl)oxy]-2-furancarboxylic acid (4.3 g; 70.6%) as a white solid after crystallization from ethyl acetate, mp 142°-144° C.

Workup

  1. customafter crystallization from ethyl acetate, mp 142°-144° C.

Sources & evidence

ORD record
ord-a67a6e1240d44c5a95800060ee60ab31
Source dataset
uspto-grants-1995_09
Patent number
US05451600

Reaction notes

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