Hydrochloric Acid → HCID 19384526, compound

Participants

Reaction Steps

The hydrolysis of 2.9 g of methyl ester from Example 156 was carried out by using the conditions described in Example 137 except that a saturated solution of oxalic acid was used for the acidification of the reaction mixture instead of 2N-HCl. There was obtained 5-[(1,2,3,4-tetrahydro-9-octyl-9H-dibenzo[b,d]pyrrol-6-yl)carbonyl]-2-furan carboxylic acid (1.4 g; 50%) after repeated crystallizations from ethyl acetate as a yellow solid, mp 140.5°-42.5° C.

Provenance & Evidence