2-Naphthalenesulfonyl chloride → HCID 19384977, compound

Participants

Reaction Steps

In a manner analogous to that of Example 5, the title compound was prepared from the Cbz amine from Example 3 and 2-naphthalenesulfonyl chloride: 1H NMR (400 MHz, CDCl3) δ8.32 (s, 1H), 7.85 (m, 3H), 7.71 (dd, 1H, J=1.8, 8.7 Hz), 7.61-7.52 (m, 2H), 7.34-7.28 (m, 5H), 6.99 (s, 4H), 6.77 (br s, 1H), 5.04 (s, 2H), 4.65 (br s, 1H), 3.33 (br q, 2H, J=5.9 Hz), 2.68 (t, 2H, J=7.0 Hz); FAB MS m/z 461 (M+1), 270.

Provenance & Evidence