反应详情

Docos-21-ynol (12 g, 0.037 mol) was dissolved in warm acetone (600 ml) treated with Jones reagent (20 ml). After stirring for 30 minutes tlc showed complete reaction so the excess Jones reagent was quenched with propane-2-ol and the volatile components removed in vacuo. The organic fractions were combined, dried (MgSO4), filtered and evaporated to leave docos-21-ynoic acid (32) as a pale green solid (10.4 g, 83%).

1. customwas quenched with propane-2-ol
2. customthe volatile components removed in vacuo
3. dry with materialdried (MgSO4)
4. filtrationfiltered
5. customevaporated