Ethylamine → HCID 14578462, compound

HRID 2400068Notes

Reaction equation

HRID 2400068 reaction equation
[O:1]1[C:3]2([CH2:8][CH2:7][CH2:6][N:5]([C:9]([O:11][CH3:12])=[O:10])[CH2:4]2)[CH2:2]1.[CH2:13]([NH2:15])[CH3:14]>>[CH2:13]([NH:15][CH2:2][C:3]1([OH:1])[CH2:8][CH2:7][CH2:6][N:5]([C:9]([O:11][CH3:12])=[O:10])[CH2:4]1)[CH3:14]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 19382148HCID 19382148, compound

Product 1

HCID 14578462HCID 14578462, compound

Procedure

9.3 g (54.3 mmol) of methyl 5-aza-1-oxaspiro[2,5]octane-5-carboxylate are added dropwise to 50 ml of ethylamine solution (50% strength in water) and the mixture is stirred overnight at room temperature. It is then concentrated and the residue is distilled.

Workup

  1. concentrationIt is then concentrated
  2. distillationthe residue is distilled

Sources & evidence

ORD record
ord-96c5e3a052fa4097afea936e0998ec51
Source dataset
uspto-grants-1995_09
Patent number
US05453422

Reaction notes

Loading…