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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400092Generated: November 1, 2026

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid → HCID 14578487, compound

https://huagongshe.com/reaction/2400092

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidHCID 5210422—
ReactantHCID 14578464HCID 14578464—
ProductHCID 14578487HCID 14578487—

Reaction Steps

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is reacted analogously to Example 1 with 3-ethylaminomethyl-3-hydroxypiperidine to give 1-cyclopropyl-7-(3-ethylaminomethyl-3-hydroxy-1-piperidinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid of melting point 199°-203°C. (with decomposition).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05453422
Source datasetuspto-grants-1995_09
ORD IDord-93922a38a8b448f99f3274788b12e746
Source noteuspto-grants-1995_09