2-Hydroxyethyl Methacrylate → HCID 10489958, compound

HRID 2400135Notes

Reaction equation

HRID 2400135 reaction equation
Cl[P:2]1(=[O:7])[O:6][CH2:5][CH2:4][O:3]1.[C:8]([O:13][CH2:14][CH2:15][OH:16])(=[O:12])[C:9]([CH3:11])=[CH2:10]>>[C:8]([O:13][CH2:14][CH2:15][O:16][P:2]1(=[O:7])[O:6][CH2:5][CH2:4][O:3]1)(=[O:12])[C:9]([CH3:11])=[CH2:10]

Participants

3

Reactant 2

HCID 133602-Hydroxyethyl MethacrylateHCID 810872-Chloro-1,3,2-dioxaphospholane 2-oxide

Product 1

HCID 10489958HCID 10489958, compound

Procedure

The 2-chloro-2-oxo-1,3,2-dioxaphospholane prepared in step (a) was reacted with 2-hydroxyethyl methacrylate to give 2-(2-oxo-1,3,2-dioxaphospholan-2-yloxy)ethyl methacrylate, as follows: Into a thoroughly dried 500 cm3 three-necked round bottomed flask equipped with a mechanical stirrer, drying tube and dropping funnel were placed 2-hydroxyethyl methacrylate (20.0 g, 0.154 mol) and triethylamine (15.6 g, 0.154 mol) was added slowly to the stirred solution, maintained at -20° C. to -15° C., over a period of 0.5 hr, whereupon triethylamine hydrochloride began to precipitate from the solution.

Sources & evidence

ORD record
ord-0f427a1be1f4493da9feb0968556b704
Source dataset
uspto-grants-1995_09
Patent number
US05453467

Reaction notes

Loading…