Methyl 3-mercaptopropionate → HCID 67780360, compound

Participants

Reaction Steps

To a stirring solution of the product of Step 4 (270 mg) and methyl 3-mercaptopropionate (250 mL) in 20 mL of CH2Cl2 was added ZnI2 (700 mg) at 0° C. The mixture was stirred for 20 min. at r.t. and then quenched with 20 mL of 25% NH4OAc, extracted with 100 mL of 2:1 Hexane/EtOAc. The organic extract was dried over Na2SO4 and concentrated. The residue was purified by flash chromatography eluted with 5:1 Hexane/EtOAc to give 320 mg of the title compound.

Provenance & Evidence