1-[3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-3-(2,2,2-trifluoro-ethyl)-urea → HCID 67027493, compound

Participants

Reaction Steps

1-(3-{7-[(E)-2-(1-Methyl-1H-imidazol-2-yl)-vinyl]imidazo[1,2-a]pyridin-3-yl}-phenyl)-3-(2,2,2-trifluoro-ethyl)-urea (86 mg) was prepared according to Procedure B3d using 3-Iodo-7-[(E)-2-(1-methyl-1H-imidazol-2-yl)-vinyl]imidazo[1,2-a]pyridine (170 mg, 0.49 mmol) and 1-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-3-(2,2,2-trifluoro-ethyl)-urea. 1H NMR (400 MHz, Me-d3-OD): 8.74 (1H, d), 8.01 (3H, d), 7.77-7.66 (2H, m), 7.64-7.50 (4H, m), 7.45-7.32 (2H, m), 4.04 (3H, s), 4.01-3.89 (2H, m). MS: [M+H]+441

Provenance & Evidence