3-Hydroxyazetidine hydrochloride → HCID 86669126, compound

HRID 2400342Notes

Reaction equation

HRID 2400342 reaction equation
C(OC(=O)N[CH:8]1[CH2:11][N:10]([C:12]2[CH:17]=[CH:16][N:15]=[C:14]([Cl:18])[N:13]=2)[CH2:9]1)(C)(C)C.Cl.N1CC([OH:25])C1>>[Cl:18][C:14]1[N:13]=[C:12]([N:10]2[CH2:11][CH:8]([OH:25])[CH2:9]2)[CH:17]=[CH:16][N:15]=1

Participants

3

Reactant 2

HCID 27592903-Hydroxyazetidine hydrochlorideHCID 86669125HCID 86669125, compound

Product 1

HCID 86669126HCID 86669126, compound

Procedure

Prepared as [1-(2-chloro-pyrimidin-4-yl)-azetidin-3-yl]-carbamic acid tert-butyl ester using azetidin-3-ol hydrochloride. MS: [M+H]+=186

Sources & evidence

ORD record
ord-1beeb169958e49de97a21af65bc1b457
Source dataset
uspto-grants-2014_08
Patent number
US08796244B2

Reaction notes

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