HCID 86694074, compound → HCID 86694075, compound

Participants

Reaction Steps

A mixture of (2S,5R)-6-(benzyloxy)-N′-(2,2-dimethylpropanoyl)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide 254 (0.32 g, 0.86 mmol) and Pd/C (0.15 g) in methanol (20 mL) was hydrogenated at 1 atm at room temperature overnight. The mixture was filtered through Celite pad and concentrated to provide 255 (0.25 g, quant. yield) as a white foam.

Provenance & Evidence