HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,8-Dibromodibenzothiophene → Tert-butyl 3-(3-bromophenyl)propylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,8-Dibromodibenzothiophene | HCID 631120 | — |
| Reactant | 1206480-72-9 | HCID 59268472 | — |
| Product | Tert-butyl 3-(3-bromophenyl)propylcarbamate | HCID 57219374 | — |
Reaction Steps
Intermediate 2,8-di(tert-butyl 3-phenylpropylcarbamate)benzothiophene was synthesized by Suzuki reaction of 2,8-dibromodibenzothiophene and tert-butyl 3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propylcarbamate, which was obtained from tert-butyl 3-(3-bromophenyl)propylcarbamate. Compound 116 was obtained following similar de-protection reaction condition in route 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796275B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-88d7bcaf36e4466b807b51afbc811f6f |
| Source note | uspto-grants-2014_08 |