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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400779Generated: October 31, 2026

1-Bromo-2-Chloroethane → HCID 58530405, compound

https://huagongshe.com/reaction/2400779

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-ChloroethaneHCID 7849—
Reactant3-FluoropyrrolidineHCID 2759163—
ReactantHCID 86659610HCID 86659610—
ProductHCID 58530405HCID 58530405—

Reaction Steps

(5Z)-3-{2-[(3R)-3-Fluoropyrrolidin-1-yl]ethyl}-5-[(1-{[4-(methyloxy)-2-(trifluoro-methyl)phenyl]methyl}-1H-indazol-5-yl)methylidene]-1,3-thiazolidine-2,4-dione was prepared from [(5Z)-5-({1-[4-methoxy-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidine (from Example 8), 1-bromo-2-chloroethane and (3R)-3-fluoropyrrolidine following General Procedure G.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796256B2
Source datasetuspto-grants-2014_08
ORD IDord-ab28421a531e4184b8b578f142b14d93
Source noteuspto-grants-2014_08