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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400782Generated: November 3, 2026

1-(2-Hydroxyethyl)piperazine → HCID 58530601, compound

https://huagongshe.com/reaction/2400782

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Hydroxyethyl)piperazineHCID 7677—
Reactant1-Bromo-2-ChloroethaneHCID 7849—
ReactantHCID 86659610HCID 86659610—
ProductHCID 58530601HCID 58530601—

Reaction Steps

(5Z)-3-{2-[4-(2-Hydroxyethyl)piperazin-1-yl]ethyl}-5-({1-[4-methoxy-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-1,3-thiazolidine-2,4-dione was prepared from [(5Z)-5-({1-[4-methoxy-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidine (from Example 8), 1-bromo-2-chloroethane and 1-(2-hydroxyethyl)piperazine following General Procedure G.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796256B2
Source datasetuspto-grants-2014_08
ORD IDord-43cd109712ec4500af9f836cc6d36885
Source noteuspto-grants-2014_08