HRID2400794

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8498

Ethanol, 2,2'-[(1-methylethyl)imino]bis-

C7H17NO2

反应SMILES：O=C1NC(=O)/C(=C/c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)S1

HCID86659608

未命名化合物

PRODUCTS

产物

$反应SMILES：CC(C)N(CCO)CCN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O$

HCID58530431

未命名化合物

PROCEDURE

实验过程

(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-{2-[(2-hydroxyethyl)(1-methylethyl)amino]ethyl}-1,3-thiazolidine-2,4-dione was prepared from [(5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidine (from Example 1) and N,N-bis(2-hydroxyethyl)isopropyl amine following General Procedure J.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-e76f6cdc78ce44ad8eb1471dbb2fdf1c
来源数据集: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US08796256B2
来源说明: uspto-grants-2014_08

反应SMILES

[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12](/[CH:16]=[C:17]4/[C:18](=[O:23])[NH:19][C:20](=[O:22])[S:21]/4)=[CH:13][CH:14]=3)[CH:9]=[N:8]2)=[C:4]([C:26]([F:29])([F:28])[F:27])[CH:3]=1.[OH:30][CH2:31][CH2:32][N:33]([CH:37]([CH3:39])[CH3:38])[CH2:34][CH2:35]O>>[Cl:1][C:2]1[CH:25]=[CH:24][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12](/[CH:16]=[C:17]4/[C:18](=[O:23])[N:19]([CH2:35][CH2:34][N:33]([CH2:32][CH2:31][OH:30])[CH:37]([CH3:39])[CH3:38])[C:20](=[O:22])[S:21]/4)=[CH:13][CH:14]=3)[CH:9]=[N:8]2)=[C:4]([C:26]([F:27])([F:29])[F:28])[CH:3]=1