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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400896Generated: November 1, 2026

N-(2-Hydroxyethyl)imidazole → 5-[1-(4-Chloro-2-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]-3-(2-imidazol-1-ylethyl)thiazolidine-2,4-dione

https://huagongshe.com/reaction/2400896

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-Hydroxyethyl)imidazoleHCID 74168—
Reactant5-[1-(4-chloro-2-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]thiazolidine-2,4-dioneHCID 86659657—
Product5-[1-(4-Chloro-2-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]-3-(2-imidazol-1-ylethyl)thiazolidine-2,4-dioneHCID 76814572—

Reaction Steps

5-[1-(4-Chloro-2-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]-3-(2-imidazol-1-ylethyl)thiazolidine-2,4-dione was prepared from 5-[1-(4-chloro-2-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]thiazolidine-2,4-dione (from Example 1) and 2-imidazol-1-ylethanol following General Procedure J.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796256B2
Source datasetuspto-grants-2014_08
ORD IDord-ff0db81e9d904d5882dd73a253498b33
Source noteuspto-grants-2014_08