HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-[4-(hydroxymethyl)oxan-4-yl]carbamate → (4-{5-[1-(2,4-Bis-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]-2,4-dioxothiazolidin-3-ylmethyl}tetrahydro-2H-pyran-4-yl)carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-[4-(hydroxymethyl)oxan-4-yl]carbamate | HCID 67114425 | — |
| Reactant | 5-[1-(2,4-bis-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]thiazolidine-2,4-dione | HCID 86659667 | — |
| Product | (4-{5-[1-(2,4-Bis-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]-2,4-dioxothiazolidin-3-ylmethyl}tetrahydro-2H-pyran-4-yl)carbamic acid tert-butyl ester | HCID 86659666 | — |
Reaction Steps
(4-{5-[1-(2,4-Bis-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]-2,4-dioxothiazolidin-3-ylmethyl}tetrahydro-2H-pyran-4-yl)carbamic acid tert-butyl ester was prepared from 5-[1-(2,4-bis-trifluoromethylbenzyl)-1H-indazol-5-ylmethylene]thiazolidine-2,4-dione (from Example 6) and (4-hydroxymethyltetrahydro-2H-pyran-4-yl)carbamic acid tert-butyl ester following General Procedure J.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796256B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-2f65a046392640bc9c90dd2e7cfdd77a |
| Source note | uspto-grants-2014_08 |