tert-butyl 1,1-dioxo-1,2,5-thiadiazolidine-2-carboxylate → HCID 58530770, compound

Participants

Reaction Steps

(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-[2-(1,1-dioxido-1,2,5-thiadiazolidin-2-yl)ethyl]-1,3-thiazolidine-2,4-dione was prepared from (5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylene)-3-(2-hydroxyethyl)thiazolidine-2,4-dione and 1,1-dioxo-1λ6-[1,2,5]thiadiazolidine-2-carboxylic acid tert-butyl ester (compound described in Chemistry—A European Journal 2004, 10(22), 5581-5606) according to General Procedure C followed by deprotection (Procedure M).

Provenance & Evidence