HCID 13759845, compound → HCID 58530846, compound

HRID 2400956Notes

Reaction equation

HRID 2400956 reaction equation
[CH3:1][NH:2][N:3]1[C:7](=[O:8])[CH2:6][S:5][C:4]1=[O:9].[Cl:10][C:11]1[CH:28]=[CH:27][C:14]([CH2:15][N:16]2[C:24]3[C:19](=[CH:20][C:21]([CH:25]=O)=[CH:22][CH:23]=3)[CH:18]=[N:17]2)=[C:13]([C:29]([F:32])([F:31])[F:30])[CH:12]=1>>[Cl:10][C:11]1[CH:28]=[CH:27][C:14]([CH2:15][N:16]2[C:24]3[C:19](=[CH:20][C:21](/[CH:25]=[C:6]4/[C:7](=[O:8])[N:3]([NH:2][CH3:1])[C:4](=[O:9])[S:5]/4)=[CH:22][CH:23]=3)[CH:18]=[N:17]2)=[C:13]([C:29]([F:30])([F:32])[F:31])[CH:12]=1

Participants

3

Reactant 2

HCID 13759845HCID 13759845, compoundHCID 866545471-(4-chloro-2-(trifluoromethyl)benzyl)-1H-indazole-5-carbaldehyde

Product 1

HCID 58530846HCID 58530846, compound

Procedure

(5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-(methylamino)-1,3-thiazolidine-2,4-dione was prepared from 3-methylaminothiazolidine-2,4-dione (from Example 357) and [4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-carbaldehyde (from Example 1) following General Procedure E.

Sources & evidence

ORD record
ord-c9a2aae0f52340e6bf335a0fa2603729
Source dataset
uspto-grants-2014_08
Patent number
US08796256B2

Reaction notes

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